Transbuccal fentanyl for rapid relief of orthopedic pain in the ED.
Transbuccal fentanyl for rapid relief of orthopedic pain in the ED. Am J Emerg Med. 2010 Oct;28(8):847-52 Authors: Shear ML, Adler JN, Shewakramani S, Ilgen J, Soremekun OA, Nelson S, Thomas SH Abstract OBJECTIVES: This study’s objectives were to assess administration of a rapidly dissolving transbuccal fentanyl tablet to patients in emergency department (ED) with [...]
Category: Pain Management Tags: Adler JN, fentanyl, Ilgen J, Nelson S, pain scale, rapid relief
Serum Bcl-2 concentrations in overweight-obese subjects with nonalcoholic fatty liver disease.
Serum Bcl-2 concentrations in overweight-obese subjects with nonalcoholic fatty liver disease. World J Gastroenterol. 2011 Dec 28;17(48):5280-8 Authors: Tarantino G, Scopacasa F, Colao A, Capone D, Tarantino M, Grimaldi E, Savastano S Abstract AIM: To shed some light on the relationship between anti-apoptotic serum Bcl-2 concentrations and metabolic status, anthropometric parameters, inflammation indices, and non-alcoholic [...]
Category: Gastroenterology Tags: apoptotic cells, chronic liver disease, concentrations, fatty liver, fatty liver disease, liver biopsy, nash, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, serum levels
Clinical features and outcomes in patients with Ewing sarcoma and regional lymph node involvement.
Clinical features and outcomes in patients with Ewing sarcoma and regional lymph node involvement. Pediatr Blood Cancer. 2011 Dec 19; Authors: Applebaum MA, Goldsby R, Neuhaus J, Dubois SG Abstract BACKGROUND: A minority of patients with Ewing sarcoma present with regional lymph node involvement. We investigated if patient characteristics and outcomes differ between patients with [...]
Category: Hematology, Oncology, Pediatrics Tags: ewing sarcoma, involvement, peripheral primitive neuroectodermal tumor, regional lymph node, regional node
The use of rapid onset opioids for breakthrough cancer pain: the challenge of its dosing.
The use of rapid onset opioids for breakthrough cancer pain: the challenge of its dosing. Crit Rev Oncol Hematol. 2011 Dec;80(3):460-5 Authors: Mercadante S Abstract Breakthrough cancer pain (BTcP) has been defined as a transitory increase in pain intensity on a baseline pain of moderate intensity in patients on analgesic treatment regularly administered. This review [...]
Category: Pain Management Tags: breakthrough cancer pain, BTcP, drug administration, efficacious treatment, moderate intensity, opioid drugs, opioids, rapid onset, slow onset
Impact of changing our cannulation method on the incidence of post-endoscopic retrograde cholangiopancreatography pancreatitis after pancreatic guidewire placement.
Impact of changing our cannulation method on the incidence of post-endoscopic retrograde cholangiopancreatography pancreatitis after pancreatic guidewire placement. World J Gastroenterol. 2011 Dec 28;17(48):5289-94 Authors: Hisa T, Matsumoto R, Takamatsu M, Furutake M Abstract AIM: To clarify whether the incidence of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) after pancreatic guidewire placement (PGW) can be reduced [...]
Category: Gastroenterology Tags: cannulation, catheter, ERCP, pancreatic cancer, pancreatic duct, pancreatitis, pancreatography, PGW, WGC
Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma.
Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma. Pediatr Blood Cancer. 2011 Dec 20; Authors: Grill J, Puget S, Andreiuolo F, Philippe C, Macconaill L, Kieran MW Abstract Diffuse intrinsic pontine gliomas (DIPG) can not be cured with current treatment modalities. Targeted therapy in this disease would benefit from advanced technologies detecting [...]
Category: Hematology, Oncology, Pediatrics Tags: blood cancer, Critical oncogenic mutations, diffuse intrinsic pontine glioma, DIPG, mutations, oncogenic, oncogenic mutations, Philippe C
Fentanyl intranasal. Breakthrough cancer pain: unsafe packaging.
Fentanyl intranasal. Breakthrough cancer pain: unsafe packaging. Prescrire Int. 2010 Nov;19(110):251 Authors: Abstract There is no firm evidence that intranasal fentanyl is more effective than buccal fentanyl. The packaging is not entirely safe, thus exposing patients and others to major risks. PMID: 21284356 [PubMed - indexed for MEDLINE] Related Journals Fentanyl buccal soluble film (Onsolis) [...]
Category: Pain Management Tags: breakthrough cancer pain, fentanyl, intranasal fentanyl
Human papillomavirus in upper digestive tract tumors from three countries.
Human papillomavirus in upper digestive tract tumors from three countries. World J Gastroenterol. 2011 Dec 28;17(48):5295-304 Authors: Castillo A, Koriyama C, Higashi M, Anwar M, Bukhari MH, Carrascal E, Mancilla L, Okumura H, Matsumoto M, Sugihara K, Natsugoe S, Eizuru Y, Akiba S Abstract AIM: To clarify human papillomavirus (HPV) involvement in carcinogenesis of the [...]
Category: Gastroenterology Tags: Anwar M, Higashi M, hpv, hpv types, human papillomavirus, Matsumoto M, squamous cell carcinomas, upper digestive tract
Initial testing of the multitargeted kinase inhibitor pazopanib by the pediatric preclinical testing program.
Initial testing of the multitargeted kinase inhibitor pazopanib by the pediatric preclinical testing program. Pediatr Blood Cancer. 2011 Dec 20; Authors: Keir ST, Morton CL, Wu J, Kurmasheva RT, Houghton PJ, Smith MA Abstract Pazopanib is an oral angiogenesis inhibitor targeting vascular growth factor receptor-1, -2, and -3, platelet derived growth factor receptor-a, platelet derived [...]
Category: Hematology, Oncology, Pediatrics Tags: angiogenesis inhibitor, Houghton PJ, kinase inhibitor, Kurmasheva RT, Morton CL, platelet derived growth factor, platelet derived growth factor receptor, vascular growth factor
Long-term dosing, safety, and tolerability of fentanyl buccal tablet in the management of noncancer-related breakthrough pain in opioid-tolerant patients.
Long-term dosing, safety, and tolerability of fentanyl buccal tablet in the management of noncancer-related breakthrough pain in opioid-tolerant patients. Curr Med Res Opin. 2011 Apr;27(4):751-60 Authors: Nalamachu SR, Narayana A, Janka L Abstract OBJECTIVE: To evaluate the long-term dosing, safety, and tolerability of fentanyl buccal tablet (FBT) in a large cohort of opioid-tolerant patients with [...]
Category: Pain Management Tags: breakthrough pain, buccal, Curr Med Res Opin, fentanyl, fentanyl buccal, patients with chronic noncancer pain, tolerability